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KMID : 1007420180160020069
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Mood and Emotion
2018 Volume.16 No. 2 p.69 ~ p.76
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Korean Medication Algorithm for Bipolar Disorder 2018 : Mixed Features
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Kim Won
Bahk Won-Myong
Yoon Bo-Hyun
Jon Duk-In
Seo Jeong-Seok
Lee Jung-Goo
Jeong Jong-Hyun
Woo Young-Sup
Kim Moon-Doo
Sohn In-Ki
Shim Se-Hoon
Song Hoo-Rim
Min Kyung-Jun
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Abstract
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Objectives : The Korean Medication Algorithm for Bipolar Disorder 2018 (KMAP-BP 2018) has been revised again as a result of a consensus of opinions among experts. The mixed episode was changed to mixed features in DSM-5. In this study, we will describe the preference and recommendation of KMAP-BP 2018 for the treatment of mood episodes with mixed features.
Methods : Out of 84 members of the review committee, 61 completed the survey. We analyzed the answers, discussed the data, and held a clinician hearing.
Results : The preferred first-step strategies for mixed features with more manic symptoms were a combination of mood stabilizers (MS), atypical antipsychotics (AAP), and AAP monotherapy. For mixed features with more depressive symptoms, a combination of MS and lamotrigine (LTG), a combination of MS and AAP, and a combination of AAP and LTG were preferred. For mixed features with manic and depressive symptoms, a combination of MS and AAP, and AAP monotherapy were preferred.
Conclusion : For mixed features, a combination of MS and AAP was generally preferred, and lamotrigine was preferred for depressive symptoms. We hope this KMAP-BP 2018 to be helpful for clinicians that treat patients with bipolar disorder in Korea.
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KEYWORD
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Bipolar disorder , KMAP-BP 2018, Mixed features
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